Articles

How true to Nature, even to their most trivial details, almost every character and every incident in the works of the great novelist whose dust has just been laid to rest, really were, is best known...

A case of novel swine influenza A (H1N1) pneumonia complicated with virus-associated hemophagocytic syndrome.

J Infect Chemother. 2012 Jan 31;

Authors: Asai N, Ohkuni Y, Matsunuma R, Iwama K, Otsuka Y, Kawamura Y, Motojima S, Kaneko N

Abstract
Influenza related to complications such as pneumonia and encephalitis have sporadically been reported. However, influenza A (H1N1)-virus-associated hemophagocytic syndrome (VAHS) has rarely been reported. A 39-year old woman complained of high fever and was referred to us. Chest infiltrations in both lungs and a positive polymerase chain reaction (PCR) for novel swine-origin influenza A (H1N1) in bronchial alveolar lavage fluid (BALF) specimen was confirmed and she was diagnosed with influenza A (H1N1) pneumonia. Pancytopenia was found, and hemophagocytic syndrome (HPS) was diagnosed by bone marrow aspiration. Following intravenous administration of antiflu drug and combination therapy of steroid pulse and erythromycin IV, the patient's respiratory dysfunction and lab data gradually improved and she was discharged on day 21. Whereas secondary HPS related to viral infections such as Epstein-Barr virus, cytomegalovirus, and human herpesvirus type 6 are commonly seen, H1N1 pneumonia complicated with secondary VAHS is rare.

PMID: 22286408 [PubMed - as supplied by publisher]

Necrotizing bronchiolitis in influenza A of swine origin (H1N1).

Am J Respir Crit Care Med. 2011 Nov 1;184(9):1086; author reply 1086

Authors: Toyoshima M, Chida K, Suda T, Sato M

PMID: 22045749 [PubMed - indexed for MEDLINE]

Clinical features of children with pneumonia from swine-origin influenza A virus H1N1: a single center experience in Japan.

Pediatr Int. 2011 Feb;53(1):115-9

Authors: Komatsu H, Sugawara H, Matsuoka M, Tsunoda T, Hirata G, Sogo T, Hatano M, Inui A, Fujisawa T

PMID: 21342340 [PubMed - indexed for MEDLINE]

bmj;344/feb08_1/e924/FIG1F1fig1As an excellent new book makes clear, migrants are a force for good.1 This is just as well: all of us are descended from the migrants who left Africa 50 000 to 60 000...

GPs should play a part in helping to coordinate better services for older people and to tackle a currently “fragmented” and inadequate system of social care, say MPs.A critical report by the...

The light suddenly went out, but the window in the wall of the theatre let us see that the un-united femoral shaft fracture was now firmly held by an old fashioned unlocked intramedullary nail,...

Fashion changes (unless you’re a chemistry teacher). Looking at photos, we cringe at what we once wore, but marvel at how much hair we had. Medicine is faddishly fickle, with trendy diagnoses, buzz...

Objective To characterise symptoms experienced by women during the transition into natural menopause, to classify women into distinct symptom profiles or trajectories, and to relate these profiles to...

Learning pointsIncidental liver lesions on medical imaging are relatively common and the vast majority are benignFatty infiltration is increasing in prevalence and can make the detection and...

A company that is based in the United States, Life Length, is offering “telomere testing and services” from its laboratory in Spain, with the aim of “making it easy for physicians and their patients...

A recently published and much publicised paper by Shapiro and colleagues, the last in a series of four, evaluated the effects of hormone therapy on the risk of breast cancer.1 The authors of the four...

The NHS faces misguided reorganisation, creeping privatisation, cuts, increased waiting lists, and stagnant wages. Although they are eerily familiar, these are not just today’s problems, but also...

bmj;344/feb08_1/e834/FIG1F1fig1The rage for breast surgery attained manic proportions in the late 19th century in the United States and Europe. But the trend was driven by surgeons, not women, and...

Joseph Sampson Gamgee (1828-1886) was one of three brothers all of whom made it into the Valhalla of British posthumous eminence, the Dictionary of National Biography. A surgeon, he is remembered...

In a pilot clinical trial, non-smokers with mild cognitive impairment were randomly allocated to receive transdermal nicotine or placebo for six months, to ascertain whether stimulation of nicotinic...

bmj;344/feb08_1/e852/FIG1F1fig1A 53 year old woman presented with a two week history of right sided limb weakness and expressive dysphasia. Magnetic resonance imaging of the brain showed a mass in...

New study doubles previous estimates of global malaria mortalityLancet2012;379:413-31bmj;344/feb08_1/e854/FIG1F1fig1In 2010, 1.24 million people worldwide died of malaria, according to the latest...

Perhaps interactions between drugs are like interactions between people: mostly inconsequential, occasionally beneficial, sometimes deadly. The principle of cancer chemotherapy before monoclonal...

Women with severe menopausal symptoms may ask their doctor how long their symptoms, particularly hot flushes and night sweats, are likely to last. To date, doctors have been able to advise only that...