The combination of two vaccines that has previously failed to produce a response on their own has cut the risk of becoming infected with HIV by more than 31 per cent.
It is the first time in human trials that a vaccine has protected against the virus which leads to Aids.
The vaccines are ALVAC, from Sanofi Pasteur, the vaccine division of French drugmaker Sanofi-Aventis; and AIDSVAX, originally developed by VaxGen Inc. and now held by Global Solutions for Infectious Diseases, a non-profit founded by some former VaxGen employees.
All the participants tested negative at the start of the trial and were given condoms, counselling and treatment for any sexually transmitted infections. They were tested every six months for HIV and any who became infected were given free treatment with antiviral medicines.
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