Milk consumption has been linked to improved health, with decreased risks of diabetes, metabolic syndrome, and colon cancer. A group of scientists in Sweden found that lactoferricin4-14 (Lfcin4-14), a milk protein with known health effects, significantly reduces the growth rate of colon cancer cells over time by prolonging the period of the cell cycle before chromosomes are replicated. In a new study, investigators report that treatment with Lfcin4-14 reduced DNA damage in colon cancer cells exposed to ultraviolet (UV) light. Their results are published in the October issue of the Journal of Dairy Science®.
Water diffusion measurements with MRI could decrease false-positive breast cancer results and reduce preventable biopsies, according to a new study published online in the journal Radiology. Researchers said the technique also could improve patient management by differentiating high-risk lesions requiring additional workup from other non-malignant subtypes.
Dynamic contrast-enhanced MRI (DCE-MRI) has emerged in recent years as a useful tool in breast cancer detection and staging. One of its primary limitations is a substantial number of false-positive findings that require biopsies.
Low levels of vitamin D and high levels of parathyroid hormone are associated with increased mortality in African American and Caucasian older adults, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism (JCEM). The study also indicates that the potential impact of remediating low vitamin D levels is greater in African Americans than Caucasians because vitamin D insufficiency is more common in African Americans.
Adolescents who sleep poorly may be at risk of cardiovascular disease in later life, according to a study in CMAJ (Canadian Medical Association Journal).
"We found an association between sleep disturbance and cardiovascular risk in adolescents, as determined by high cholesterol levels, increased BMI [body mass index] and hypertension," writes lead author Dr. Indra Narang, respirologist and director of sleep medicine at The Hospital for Sick Children (SickKids), Toronto, Ontario, with coauthors. "These findings are important, given that sleep disturbance is highly prevalent in adolescence and that cardiovascular disease risk factors track from childhood into adulthood."
Researchers from the University of Alicante (Spain) have analysed ten brands of cigarettes and found that the concentrations of certain harmful and carcinogenic substances vary significantly from one brand to another. Until now legislation has not covered these compounds and only establishes limits for nicotine, tar and carbon monoxide. Scientists have also developed catalysts to reduce the harmful products in tobacco.
Researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have found a new genetic mutation responsible for deafness and hearing loss associated with Usher syndrome type 1.
These findings, published in the Sept. 30 advance online edition of the journal Nature Genetics, could help researchers develop new therapeutic targets for those at risk for this syndrome.
Partners in the study included the National Institute on Deafness and other Communication Disorders (NIDCD), Baylor College of Medicine and the University of Kentucky.
Usher syndrome is a genetic defect that causes deafness, night-blindness and a loss of peripheral vision through the progressive degeneration of the retina.