Our experiences -- the things we see, hear, or do -- can trigger long-term changes in the strength of the connections between nerve cells in our brain, and these persistent changes are how the brain encodes information as memory. As reported in Neuron, Johns Hopkins researchers have discovered a ne
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Researchers at the University of Pennsylvania School of Medicine are the first to observe and measure the internal motion inside proteins, or its "dark energy." This research, appearing in the current issue of Nature has revealed how the internal motion of proteins affects their function and overtu
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Lung transplants have been performed successfully for more than 20 years in humans but never before in mice -- until now. Surgeons at Washington University School of Medicine in St. Louis have developed the first mouse model of lung transplantation, and they're hoping it will help explain why the s
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A fat-derived protein known for its effects on the liver and skeletal muscle might also serve as an energy-conserving signal to the brain during periods of starvation, suggests a new study in the July issue of Cell Metabolism, a publication of Cell Press. The substance, known as adiponectin, acts o
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In her Brown University laboratory, Edith Mathiowitz makes tiny particles coated in polymers. These microcapsules, some as small as the point of a pin, can carry medicines, genes, paints, pesticides -- any molecule that needs protection or controlled release.Mathiowitz developed her technique as a
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A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains -- unveiled layer by layer -- by extending the capabilities of conventional magnetic resonance imaging."These images can be more than 100,000 times higher resolution t
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In a study publishing in PLoS Computational Biology, Shakhnovich et al present a new model of early biological evolution - the first that directly relates the fitness of a population of evolving model organisms to the properties of their proteins. [click link for full article]
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While most RNAs work to create, package, and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a
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Although a number of studies have suggested that regular exercise reduces inflammation -- a condition that is predictive of cardiovascular and other diseases, such as diabetes -- it is still not clear whether there is a definitive link. And if such a link exists, the nature of the relationship is b
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