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Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in The EMBO Journal this week. Blocking the action of this protein could help to prevent the formation of metastases by reducing tumour cell prolif read more »
Source:http://www.medicalnewstoday.com
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Why do so many people continue to suffer from life-altering, chronic pain long after their injuries have actually healed"The definitive answer -- and an effective treatment -- has long eluded scientists. Traditional analgesic drugs, such as aspirin and morphine derivatives, haven't worked very well read more »
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Scientists from the Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of "Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like P read more »
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Inflammation of the pancreas (pancreatitis), which is due to the breakdown of pancreatic tissue by its own enzymes, is a common clinical problem. Activation of the signaling pathway involving NF-kappaB and the inhibitor of NF-kappaB (IKK), resulting in the expression of proinflammatory molecules, i read more »
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Holoprosencephaly (HPE) is caused by the failure of an embryo's forebrain to divide to form the distinct left and right halves of the brain, causing defects in the development of the face and in the structure and function of the brain. The most severe form of facial defects is cyclopia, in which on read more »
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Resistin is a small protein secreted by the immune cells monocytes and macrophages, and has been linked to insulin resistance, atherosclerosis, and inflammation. Recently, studies in mice have shown that resistin is present in the mouse hypothalamus and that it is capable of activating specific neu read more »
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Researchers have discovered a new cellular mechanism that may better explain what causes amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease.ALS is characterized by the death of neurons that control voluntary muscles, leading to muscle weakness and atrophy. [click link for full read more »
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Researchers provide new details about how proteins orchestrate cell division.Cells can divide only when certain key proteins are activated and others inhibited. A protein called NIPA and a set of two proteins called cyclin B1 and Cdk1 are some of these key proteins. Until now, scientists had shown read more »
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Effector proteins are the bad guys that help bacterial pathogens do their job of infecting the host by crippling the body's immune system. In essence, they knock down the front door of resistance and disarm the cell's alarm system. [click link for full article] read more »
Source:http://www.medicalnewstoday.com
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