Objective To examine concordance between treatment effects in animal experiments and clinical trials.Study design Systematic review.Data sources Medline, Embase, SIGLE, NTIS, Science Citation Index, CAB, BIOSIS.Study selection Animal studies for interventions with unambiguous evidence of a treatment...
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Source:http://www.bmj.com DiscussBury
Objective To evaluate the performance of a routine incident reporting system in identifying patient safety incidents.Design Two stage retrospective review of patients' case notes and analysis of data submitted to the routine incident reporting system on the same patients.Setting A large NHS hospita
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Source:http://www.bmj.com DiscussBury
Objective To examine the relation between IQ in childhood and vegetarianism in adulthood.Design Prospective cohort study in which IQ was assessed by tests of mental ability at age 10 years and vegetarianism by self-report at age 30 years.Setting Great Britain.Participants 8170 men and women aged 30 ...
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Source:http://www.bmj.com DiscussBury
Objective To compare the risk of suicide in adults using the antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin.Design Retrospective cohort study.Setting UK General Practice Research Database. Participants 219 088 patients, aged 18-89 years, who were prescribed venlafaxin...
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Source:http://www.bmj.com DiscussBury
Objectives To identify women who survived breast cancer and subsequently conceived and to determine the rate of pregnancy (proportion), management, outcome of the cancer, and outcome of the first subsequent pregnancy.Design Population based descriptive study with cases identified from the Western Au...
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Source:http://www.bmj.com DiscussBury
Objective To determine whether providing mothers of babies in neonatal intensive care units with audiotapes of their conversations with a neonatologist improves recall of information and psychological wellbeing.Design Randomised, single blinded trial.Setting Neonatal intensive care unit, North Queen...
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Source:http://www.bmj.com DiscussBury
Objective To assess the impact of a theoretically based sex education programme (SHARE) delivered by teachers compared with conventional education in terms of conceptions and terminations registered by the NHS.Design Follow-up of cluster randomised trial 4.5 years after intervention. Setting NHS r
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Source:http://www.bmj.com DiscussBury
Objective To evaluate the effectiveness of self management as a first line intervention for men with lower urinary tract symptoms.Design Randomised controlled trial.Setting A teaching hospital and a district general hospital in London.Participants 140 men (mean age 63 (SD 10.7) years), recruited bet...
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Source:http://www.bmj.com DiscussBury
Psychoanalytic therapies have been in professional use for over a century, but a new study from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center is the first to show that a classic psychoanalytic talk therapy is efficacious in treating panic disorder. Panic disorder...
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Source:http://www.medicalnewstoday.com DiscussBury
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